Update firmware for your printer and software that you are using
Make sure the .gx file was sliced for your printer model and nozzle size (FlashForge printers will try to print .gx files that aren't made for them - they won't work well!)
Calibrate your printer / level the bed
Wash the bed with dishwashing liquid and dry - even if it looks clean (there could be oils etc from your fingers)
If printing PLA, increase the bed temperature to 60-70 degrees celsius
Try changing to a new roll of filament - this is more art than science. Filament is weird and gets affected by lots of things: bad batch, absorbs water, different colored filament of the same brand etc.
Watch the first layer go down - if you can see it not being completely flat (i.e. bits of plastic sticking up), it could be a partial clog in your nozzle. The bits sticking up get caught by the nozzle on the second layer and detach it. If you have another nozzle try swapping that in, or else you could try cleaning your nozzle with a cleaning needle.
Use a glue stick or hairspray
Use a raft
Factory reset your printer
Having adhesion troubles? Try these things
Written by Jon Soong
Updated yesterday